Zolucatetide
Zolucatetide (FOG-001; I-66) is a potent β-catenin inhibitor with an IC50 of β-catenin and T-cell factor (TCF) transcription factor interaction. Zolucatetide inhibits cell proliferation and induces cell cycle arrest in target cells. Zolucatetide exhibits anti-tumor efficacy in mice bearing COLO320DM colon cancer cell (with APC, TP53 mutations) xenografts. Zolucatetide can be used for the study of colon cancer[1].
Product Specifications
CAS Number
3044032-95-0
Product Name Alternative
FOG-001; I-66
UNSPSC
12352209
Target
β-catenin
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.31
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
Molecular Formula
C102H134N18O25S2
Molecular Weight
2076.39
References & Citations
[1]Brian Halbert WHITE, et al. Stapled peptides and methods thereof. WO2022261257A1.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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