KYS-1

KYS-1 is a selective substrate for cathepsin E with a Km value of 1.9 μM. KYS-1 was incubated with cathepsin E (1.0 ng) with the pH optimum of approximately pH 4.0[1].

Product Specifications

CAS Number

[592544-81-5]

UNSPSC

12352209

Target

Cathepsin

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Smiles

O=C([C@@H](NC(CNC(CC(C1=CC=C(C=C1O2)OC)=CC2=O)=O)=O)CO)N3[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](CCCNC(N)=N)C(N)=O)=O)CCCCNC5=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C5)=O)C)=O)CC(C)C)=O)=O)C)=O)CCC3

Molecular Formula

C61H82N16O18

Molecular Weight

1327.40

References & Citations

[1]Yoshiyuki Yasuda, et al. A new selective substrate for cathepsin E based on the cleavage site sequence of alpha2-macroglobulin. Biol Chem. 2005 Mar;386 (3) :299-305.