Cathepsin E substrate e

Cathepsin E substrate e is a substrate of Cathepsin E. Cathepsin E substrate e was designed in such a way that due to the close proximity of a Mca-donor and a Dnp-acceptor, a near complete intramolecular quenching effect was achieved in its intact state. After the proteolytic cleavage of the hydrophobic motif of the peptide substrate, both Mca and Dnp would be further apart, resulting in bright fluorescence[1].

Product Specifications

CAS Number

[1246741-19-4]

UNSPSC

12352209

Target

Cathepsin

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Smiles

O=C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CC(C1=CC=C(C=C1O2)OC)=CC2=O)=O)C)=O)=O)CC3=CC=CC=C3)=O)CO)=O)CC(C)C)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](CCCNC(N)=N)C(N)=O)=O)CCCCNC5=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C5)=O)C)=O)CCC4