IETP2
IETP2 targets low-density lipoprotein receptor-related protein 1 (LRP1) with a KD of 738 nM and can be used for drug- and imaging agents delivery across the blood-labyrinth barrier (BLB) [1].
Product Specifications
CAS Number
2314338-36-6
UNSPSC
12352209
Target
LDLR
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Smiles
O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=C(C=C2)O)C(NCC(NCC(N[C@@H](CCCNC(N)=N)C(N3[C@@H](CCC3)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N
Molecular Formula
C107H171N39O29
Molecular Weight
2467.75
References & Citations
[1]Shi X, et al., LDL receptor-related protein 1 (LRP1), a novel target for opening the blood-labyrinth barrier (BLB) . Signal Transduct Target Ther. 2022 Jun 10;7 (1) :175.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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