NOTA-P2-RM26
NOTA-P2-RM26 is an antagonist of Bombesin analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT[1].
Product Specifications
CAS Number
1446005-10-2
UNSPSC
12352209
Target
Bombesin Receptor
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
97.20
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(CN(CCN(CC1)CC(O)=O)CCN1CC(NCCOCCOCC(N[C@H](CC2=CC=CC=C2)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](C)C(N[C@@H](C(C)C)C(NCC(N[C@H](C(N[C@@H](CC(C)C)[C@@H](O)CC(N[C@H](C(N)=O)CC(C)C)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)CC4=CNC5=CC=CC=C45)=O)=O)=O)=O)=O
Molecular Formula
C73H110N18O19
Molecular Weight
1543.76
References & Citations
[1]Varasteh Z, et al. Synthesis and characterization of a high-affinity NOTA-conjugated bombesin antagonist for GRPR-targeted tumor imaging. Bioconjug Chem. 2013 Jul 17;24 (7) :1144-53.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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