UK140
UK140 is the inhibitor for urokinase-type plasminogen activator (uPA) with Ki of 0.20 µM and 2.79 µM for huPA anf muPA. UK140 can be used in metastasis-related research[1].
Product Specifications
UNSPSC
12352209
Target
PAI-1
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C([C@@H](N)C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(O)=O)=O)CSC2)=O)CO)=O)CO)=O)CCC1)=O)CC(O)=O)=O)C(C)C)=O)=O)CSC3)=O)=O)CO)=O)CC4=CC=CC=C4)=O)CCCCN)=O)CO)=O)CC(N)=O)=O)CSCC5=CC2=CC3=C5
Molecular Formula
C72H105N19O25S3
Molecular Weight
1732.91
References & Citations
[1]Mazzocato Y, et al., A novel genetically-encoded bicyclic peptide inhibitor of human urokinase-type plasminogen activator with better cross-reactivity toward the murine orthologue. Bioorg Med Chem. 2023 Nov 15;95:117499.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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