P315V3
P315V3 is an pan inhibitor for coronavirus, that inhibits SARS-CoV-2 prototypePT, Delta, BA.1 and BA.4 strain with IC50s of 10.9, 8.9, 8.6, and 2.7 nM. P315V3 exhibits cytotoxicity in Vero cell with CC50 of 4.3 μM. P315V3 exhibits anti-infectious efficacy in mouse models[1].
Product Specifications
UNSPSC
12352209
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C([C@@H](N)C(C)C)N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(NCCOCCOCCOCCOCC(O[C@H]1CC[C@]2(C)[C@]([C@@]3([H])CC=C2C1)(CC[C@@]4(C)[C@@]3([H])CC[C@@]4([C@@H](CCCC(C)C)C)[H])[H])=O)=O)CS)=O)=O)CO)=O)=O)CO)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CC(O)=O)=O)[C@H](CC)C)=O)CC(C)C)=O)CO)=O)CCC(O)=O)=O)CC(N)=O)=O)CC(C)C)=O)CC(N)=O)=O)CCCCN)=O)C)=O)C(C)C)=O)CCC(O)=O)=O)CC(N)=O)=O)CC(C)C)=O)CCCNC(N)=N)=O)CC(O)=O)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCCCN)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CC(N)=O)=O)C(C)C)=O)C(C)C)=O)CO)=O)C)=O)CC(N)=O)=O)[C@H](CC)C)=O)=O)CO)=O)[C@H](CC)C)=O)CC(O)=O)=O)=O)CC(C)C)=O)CC(O)=O
Molecular Formula
C241H407N59O80S
Molecular Weight
5443.22
References & Citations
[1]Wu L, et al., A pan-coronavirus peptide inhibitor prevents SARS-CoV-2 infection in mice by intranasal delivery. Sci China Life Sci. 2023 Oct;66 (10) :2201-2213.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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