CTEV6-2
CTEV6-2 binds to the cysteine residue (C151) of tobacco etch virus protease (TEV protease), and covalently inhibits TEV protease with an IC50 of 81.7 nM[1].
Product Specifications
UNSPSC
12352209
Target
Virus Protease
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CCC([C@@H]1NC([C@H](CSC/C(CSC[C@H](NC(CNC([C@@H](NC1=O)CC2=CC3=C(N2)C=CC=C3)=O)=O)C(NCC(N)=O)=O)=N\OCC(NC/C=C/S(C)(=O)=O)=O)NC([C@@H](NC([C@@H]4CCCN4C([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CO)N)=O)CC(O)=O)=O)CC(N)=O)=O)CCC(O)=O)=O)=O)CC(C)C)=O)=O)C
Molecular Formula
C63H93N17O22S3
Molecular Weight
1536.71
References & Citations
[1]Lan T, et al., Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display. J Am Chem Soc. 2024 Aug 28;146 (34) :24053-24060.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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