Pegtarazimod
Pegtarazimod (RLS-0071) is an inhibitor for Complement system via classical and lectin pathways. Pegtarazimod inhibits myeloperoxidase (MPO), reduces ROS generation. Pegtarazimod reduces the formation of neutrophil extracellular traps (NETs) . Pegtarazimod exhibits anti-inflammatory activity and can be used in research of acute graft-versus-host disease[1].
Product Specifications
CAS Number
2056232-82-5
Product Name Alternative
RLS-0071
UNSPSC
12352209
Target
Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Inflammation/Immunology
Smiles
O=C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N1[C@@H](CCC1)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CS)C(N[C@@H](CS)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](C)C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)N
Molecular Formula
C122H224N20O46S2
Molecular Weight
2771.32
References & Citations
[1]Holzmüller V, et al. Exploring a Novel Anti-Inflammatory Peptide As a Potential Treatment for Acute Graft-Versus-Host Disease (aGVHD) [J]. Blood, 2024, 144: 3399.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Phase 2
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6399562-01 0.1 mL
ANXA11 (Annexin A11, Annexin-11, Annexin XI, Calcyclin-associated Annexin 50, CAP-50, 56kD Autoantigen, ANX11) (HRP)
Sign In for Pricing
View Details MBS6399562-02 5x 0.1 mL
ANXA11 (Annexin A11, Annexin-11, Annexin XI, Calcyclin-associated Annexin 50, CAP-50, 56kD Autoantigen, ANX11) (HRP)
Sign In for Pricing
View Details 
MBS2906797-01 48 Well
Human ENTPD6/Ectonucleoside triphosphate diphosphohydrolase 6 ELISA Kit
Sign In for Pricing
View Details MBS2906797-02 96 Well
Human ENTPD6/Ectonucleoside triphosphate diphosphohydrolase 6 ELISA Kit
Sign In for Pricing
View Details MBS2906797-03 5x 96 Well
Human ENTPD6/Ectonucleoside triphosphate diphosphohydrolase 6 ELISA Kit
Sign In for Pricing
View Details MBS2906797-04 10x 96 Well
Human ENTPD6/Ectonucleoside triphosphate diphosphohydrolase 6 ELISA Kit
Sign In for Pricing
View Details