S1b3inL1

S1b3inL1 is a SARS-CoV-2 spike protein macrocyclic peptide inhibitor. S1b3inL1 can bind the conserved site of spike protein with high affinity and inhibit the infection of various SARS-CoV-2 variant strains. S1b3inL1 has antiviral activity[1].

Product Specifications

CAS Number

[3027437-21-1]

UNSPSC

12352209

Target

SARS-CoV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H]1CCCN1C([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(C=C2)O)N3)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CCC(N)=O)=O)[C@@H](C)CC)=O)[C@@H](C)CC)=O)[C@@H](C)CC)=O)=O)CO)=O)CC(C)C)=O)CC4=CNC5=CC=CC=C45)=O)C(C)C)=O)CC6=CC=CC=C6)=O)CSCC3=O)=O)N

Molecular Formula

C103H158N30O24S

Molecular Weight

2232.61

References & Citations

[1]Thijssen V, et al. A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein. Proc Natl Acad Sci U S A. 2023 Jun 27;120 (26) :e2303292120.