LAG-3 cyclic peptide inhibitor 12
Selected Variant
HY-P10837
Size: 1 Each
LAG-3 cyclic peptide inhibitor 12 (Cyclic peptide 12) is an inhibitor of LAG-3 with an IC50 value of 4.45 μM and a Ki value of 2.66 µM[1].
Product Specifications
UNSPSC
12352209
Target
LAG-3
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CCSC)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC2=CC=CC(C#N)=C2)C(N[C@@H](CCCNC(N)=N)C(N[C@H]3C)=O)=O)=O)=O)=O)=O)[C@H](CSSC[C@@H](C(O)=O)NC3=O)N
Molecular Formula
C44H67N13O11S3
Molecular Weight
1050.28
References & Citations
[1]Calvo-Barreiro L, et al. Design and Biophysical Characterization of Second-Generation cyclic peptide LAG-3 inhibitors for cancer immunotherapy. Bioorg Med Chem Lett. 2024 Nov 15;113:129979.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PA2057-FITC 100 µg/Vial
Anti-CD244 Antibody Picoband®, FITC Conjugate
Sign In for Pricing
View Details 
BNC401504-100 1x 100 µL
ALK (Anaplastic Lymphoma Kinase) / CD246 (ALK/1504), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
A08381-1-Cy3 100 µg/Vial
Anti-CLDN11 Antibody Picoband®, Cy3 Conjugate
Sign In for Pricing
View Details 
A04526-1-Cy3 100 µg/Vial
Anti-RAB11B Antibody Picoband®, Cy3 Conjugate
Sign In for Pricing
View Details 
BNC680991-100 1x 100 µL
SOX10 (SOX10/991), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details