PD-1/PD-L1 inhibitory peptide C8
PD-1/PD-L1 inhibitory peptide C8 is inhibits PD-1/PD-L1 interaction, promotes the activation of CD8+ and CD4+ T cells, and increases the IFN-γ secretion. PD-1/PD-L1 inhibitory peptide C8 exhibits antitumor efficacy in mouse model[1].
Product Specifications
UNSPSC
12352209
Target
PD-1/PD-L1
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
O=C(N[C@@H](CCCCN)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CCCNC(N)=N)C(N4[C@@H](CCC4)C(N[C@@H](CO)C(N[C@H]5CCC(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CSSC[C@@H](C(O)=O)NC5=O)N
Molecular Formula
C51H72N14O14S2
Molecular Weight
1169.33
References & Citations
[1]Zhai W, et al., Blocking of the PD-1/PD-L1 interaction by a novel cyclic peptide inhibitor for cancer immunotherapy. Sci China Life Sci. 2021 Apr;64 (4) :548-562.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Mouse Monoclonal HLA DRB1 Antibody (DA2) [Biotin]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
NB100-2705B 0.1 mL
Mouse Monoclonal HLA DRB1 Antibody (DA2) [Biotin]
Sign In for Pricing
View Details ![[Mpr4, D-Ala6, D-Ala13]-BNP (4-26) amide / PL081 (Porcine)](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
011-13 200 µg
[Mpr4, D-Ala6, D-Ala13]-BNP (4-26) amide / PL081 (Porcine)
Sign In for Pricing
View Details 
bs-42187P-APC-01 20 µg
Recombinant human FIBIN protein, N-Trx-His, APC Conjugated
Sign In for Pricing
View Details bs-42187P-APC-02 100 µg
Recombinant human FIBIN protein, N-Trx-His, APC Conjugated
Sign In for Pricing
View Details bs-42187P-APC-03 500 µg
Recombinant human FIBIN protein, N-Trx-His, APC Conjugated
Sign In for Pricing
View Details 
YP-W34752-01 48 Tests
Rat Transforming Growth factor β3 (TGF-β3) ELISA Kit
Sign In for Pricing
View Details