Polyglutamine binding peptide 1
Polyglutamine binding peptide 1 (QBP1) is a peptide inhibitor of polyglutamine (polyQ) . Polyglutamine binding peptide 1 inhibits polyQ protein aggregation in vitro and suppresses polyQ-induced cell death in cell culture[1].
Product Specifications
CAS Number
274914-75-9
UNSPSC
12352209
Target
Huntingtin
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(N[C@@H](CC(N)=O)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N7[C@@H](CCC7)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC8=CC=CC=C8)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N
Molecular Formula
C72H90N16O16
Molecular Weight
1435.58
References & Citations
[1]Yoshitaka Nagai, et al. Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila. Hum Mol Genet. 2003 Jun 1;12 (11) :1253-9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
