CP61
CP61, a cyclic peptide, is a dual CtBP1/CtBP2 inhibitor. CP61 binds CtBP1 with 3 μM affinity. CP61 inhibits the heterodimerization and homodimerization of CtBP2 with an IC50 value of 19 μM. CP61 is promising for research of cancers[1].
Product Specifications
CAS Number
1631984-43-4
UNSPSC
12352209
Target
Others
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C([C@@H](NC1=O)CO)NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CC2=CC=C(O)C=C2)=O)CCSC)=O)CCCNC(N)=N)=O)C(C)C)=O)C(C)C)=O)[C@@H](C)O)=O)CC3=CNC4=CC=CC=C34)=O
Molecular Formula
C50H73N13O12S
Molecular Weight
1080.26
References & Citations
[1]Birts CN, et al. A cyclic peptide inhibitor of C-terminal binding protein dimerization links metabolism with mitotic fidelity in breast cancer cells. Chem Sci. 2013 Aug 1;4 (8) :3046-3057.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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