VAMP
VAMP, a tetrapeptide, is a competitive dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 1.00 μM and a Kd of 6.89 μM. VAMP effectively targets the DPP-IV-GLP-1 axis and can be used for the study of type 2 diabetes[1].
Product Specifications
UNSPSC
12352209
Target
Dipeptidyl Peptidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Purity
98.13
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](C)C(N[C@@H](CCSC)C(N1[C@@H](CCC1)C(O)=O)=O)=O)[C@H](C(C)C)N
Molecular Formula
C18H32N4O5S
Molecular Weight
416.54
References & Citations
[1]Haihong Chen, et al. A novel bifunctional peptide VAMP mined from hemp seed protein hydrolysates improves glucose homeostasis by inhibiting intestinal DPP-IV and increasing the abundance of Akkermansia muciniphila. bioRxiv. July 23, 2024.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10809/VAMP-SDS-MedChemExpress.pdf
Scientific Category
Peptides
Clinical Information
Phase 2
Isoform
DPP-4
Available Sizes
Curated Selection
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