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VAMP

VAMP, a tetrapeptide, is a competitive dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 1.00 μM and a Kd of 6.89 μM. VAMP effectively targets the DPP-IV-GLP-1 axis and can be used for the study of type 2 diabetes[1].

Product Specifications

UNSPSC

12352209

Target

Dipeptidyl Peptidase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Purity

98.13

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](C)C(N[C@@H](CCSC)C(N1[C@@H](CCC1)C(O)=O)=O)=O)[C@H](C(C)C)N

Molecular Formula

C18H32N4O5S

Molecular Weight

416.54

References & Citations

[1]Haihong Chen, et al. A novel bifunctional peptide VAMP mined from hemp seed protein hydrolysates improves glucose homeostasis by inhibiting intestinal DPP-IV and increasing the abundance of Akkermansia muciniphila. bioRxiv. July 23, 2024.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

Phase 2

Isoform

DPP-4

Available Sizes

Frequently Asked Questions

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