P160 peptide
The P160 peptide is a breast cancer-targeting peptide that binds to the keratin 1 (KRT1) receptor on breast cancer cells, with a Kd of approximately 1.1 μM, demonstrating significant potential for targeted drug delivery to breast cancer cells. The P160 peptide enhances the cellular uptake and anticancer activity of the pro-apoptotic antimicrobial peptide MccJ25 (microcin J25) . The P160 peptide can be used in cancer research[1].
Product Specifications
CAS Number
362043-77-4
UNSPSC
12352209
Target
Microtubule/Tubulin
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C([C@H]1N(CCC1)C([C@@H](N)C(C)C)=O)N[C@H](C(N[C@@H](CCSC)C(N[C@@H](CCC(O)=O)C(N2[C@@H](CCC2)C(N[C@@H](C)C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CC3=CC=CC=C3)=O)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56
Molecular Formula
C74H105N17O17S
Molecular Weight
1536.79
References & Citations
[1]Soudy R, et al. Breast Cancer Targeting Peptide Binds Keratin 1: A New Molecular Marker for Targeted Drug Delivery to Breast Cancer. Mol Pharm. 2017 Mar 6;14 (3) :593-604.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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