CK3 peptide

CK3 peptide is an NRP-1 targeting peptide with the amino acid sequence CLKADKAKC. The CK3 peptide specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging show significant accumulation of CK3 peptide in xenograft tumors in nude mice. CK3 peptide can be used for molecular imaging studies of breast cancer.

Product Specifications

CAS Number

[1801552-75-9]

UNSPSC

12352209

Target

Complement System

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C([C@@H](N)CSSC[C@H](NC1=O)C(O)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CCCCN)=O)C)=O)CCCCN)=O)CC(O)=O)=O)C)=O)CCCCN)=O)CC(C)C

Molecular Formula

C40H72N12O12S2

Molecular Weight

977.20

References & Citations

[1]Feng GK, et al. SPECT and near-infrared fluorescence imaging of breast cancer with a neuropilin-1-targeting peptide. J Control Release. 2014 Oct 28;192:236-42.