Sifuvirtide (acetate)

Sifuvirtide (SFT) acetate is a potent HIV fusion inhibitor. Sifuvirtide acetate inhibits HIV-1 mediated cell fusion in a dose-dependent manner and is highly potent against infection by primary and laboratory-adapted HIV-1 isolates of multiple genotypes. Sifuvirtide acetate can be used in the research of anti-HIV drugs[1].

Product Specifications

Product Name Alternative

SFT (acetate)

UNSPSC

12352209

Target

HIV

Related Pathways

Anti-infection

Field of Research

Infection

Purity

99.82

Smiles

O=C(C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCC(O)=O)=O)CC(C)C)=O)CC(C)C)=O)CC(O)=O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CC(N)=O)=O)CCCNC(N)=N)=O)CC(O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(O)=O)=O)CCC(N)=O)=O)CO)=O)CCC(O)=O)=O)CCC(O)=O)=O)CC(C)C)=O)[C@H](CC)C)=O)CCCNC(N)=N)=O)CC1=CC=C(O)C=C1)=O)[C@H](CC)C)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)[C@@H](C)O)=O)CC2=CC=C(O)C=C2)=O)CC(N)=O)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CC3=CNC4=CC=CC=C34)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CC5=CNC6=CC=CC=C56)=O)CO.CC(O)=O.[x]

Molecular Formula

C203H309N59O72.xC2H4O2

Molecular Weight

4727.98 (free base)

References & Citations

[1]Wang R R, et al. Sifuvirtide, a potent HIV fusion inhibitor peptide[J]. Biochemical and biophysical research communications, 2009, 382 (3) : 540-544.