Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

A11 (acetate)

A11 (ANXA1-derived 11 amino acid-long peptide) acetate is an ANXA1-EphA2 interaction blocker peptide. A11 acetate decreases ANXA1 bound to EphA2 and increased Cbl (an E3 ubiquitin ligase of EphA2) bound to EphA2. A11 efficiently decreases EphA2 level, and substantially increases EphA2 ubiquitination. A11 acetate increases EphA2 internalization and colocalization of EphA2 and Cbl in the NPC cells. A11 acetate inhibits nasopharyngeal carcinoma (NPC) cell proliferation, migration and invasion. A11 acetate inhibits angiogenesis[1].

Product Specifications

UNSPSC

12352211

Target

Ephrin Receptor

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Purity

98.48

Smiles

OC1=CC=C(C=C1)C[C@@H](C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CCC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC(CNC([C@@H](N)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O.[x]

Molecular Formula

C117H204N46O32.xC2H4O2

Molecular Weight

2767.16 (free base)

References & Citations

[1]Feng J, et al. ANXA1 Binds and Stabilizes EphA2 to Promote Nasopharyngeal Carcinoma Growth and Metastasis. Cancer Res. 2020 Oct 15;80 (20) :4386-4398.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

GPR142 (NM_181790) Human Tagged ORF Clone Lentiviral Particle
RC224208L2V 200 µL

GPR142 (NM_181790) Human Tagged ORF Clone Lentiviral Particle

Sign In for Pricing
View Details
WT2 3'UTR Lenti-reporter-Luc Vector
50476081 1.0 µg

WT2 3'UTR Lenti-reporter-Luc Vector

Sign In for Pricing
View Details
LOC689840 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)
LV643752 1.0 µg DNA

LOC689840 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

Sign In for Pricing
View Details
Mouse C-C Motif Chemokine 3 (CCL3) Protein
abx654240-01 10 µg

Mouse C-C Motif Chemokine 3 (CCL3) Protein

Sign In for Pricing
View Details
Mouse C-C Motif Chemokine 3 (CCL3) Protein
abx654240-02 50 µg

Mouse C-C Motif Chemokine 3 (CCL3) Protein

Sign In for Pricing
View Details
Mouse C-C Motif Chemokine 3 (CCL3) Protein
abx654240-03 100 µg

Mouse C-C Motif Chemokine 3 (CCL3) Protein

Sign In for Pricing
View Details