Palopegteriparatide
Palopegteriparatide (Transcon PTH) is a prodrug of parathyroid hormone PTH 1-34, which can maintain normal and stable calcium concentrations without the need for calcium and active vitamin D replacement. Palopegteriparatide can be used in research on hypoparathyroidism[1][2].
Product Specifications
CAS Number
2222514-07-8
Product Name Alternative
Transcon PTH; ACP-014
UNSPSC
12352209
Target
Others
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Solubility
10 mM in DMSO
Smiles
[{X}-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe(X=O-methylpolyethyleneglycol(2x20kDamPEG)-Aib)]
References & Citations
[1]Khan AA, et al. Efficacy and Safety of Parathyroid Hormone Replacement With TransCon PTH in Hypoparathyroidism: 26-Week Results From the Phase 3 PaTHway Trial. J Bone Miner Res. 2023;38 (1) :14-25.|[2]Kontogeorgos G. Parathyroid Hormone Hyper-and Hypoparathyroidism Effect of Treatment and Long-term Follow-up Studies[M]. 2024.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Launched
Frequently Asked Questions
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