[Phe1Ψ (CH2-NH) Gly2]Nociceptin (1-13) NH2
[Phe1Ψ (CH2-NH) Gly2]Nociceptin (1-13) NH2 is a nociceptin receptor (ORL1) agonist. [Phe1Ψ (CH2-NH) Gly2]Nociceptin (1-13) NH2 strongly depresses the nociceptive flexor reflex in rats. [Phe1Ψ (CH2-NH) Gly2]Nociceptin (1-13) NH2 can be used for analgesia research[1].
Product Specifications
CAS Number
213130-17-7
UNSPSC
12352209
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
NCCCC[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](CO)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC(CNC([C@H]([C@H](O)C)NC([C@H](CC1=CC=CC=C1)NC(CNC(CNC[C@@H](N)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C61H102N22O14
Molecular Weight
1367.60
References & Citations
[1]Xu IS, et al. [Phe1psi (CH2-NH) Gly2]-nociceptin- (1-13) NH2, a proposed antagonist of the nociceptin receptor, is a potent and stable agonist in the rat spinal cord. Neurosci Lett. 1998 Jun 19;249 (2-3) :127-30.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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