Cibinetide (acetate)

Cibinetide (ARA290) acetate is an erythropoietin (EPO) derivative that acts as a specific agonist of the erythropoietin/CD131 heteroreceptor. ICibinetide acetate can be used in the research of neurological disorders[1][2][3].

Product Specifications

Product Name Alternative

ARA290 (acetate)

UNSPSC

12352209

Target

Transmembrane Glycoprotein

Related Pathways

Immunology/Inflammation

Field of Research

Neurological Disease

Smiles

OC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H]1CCC(N1)=O)=O)CCC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)C)=O)CC(C)C)=O)CC(N)=O)=O)CO)=O)CO)=O.CC(O)=O.[x]

Molecular Formula

C51H84N16O21.xC2H4O2

Molecular Weight

1257.31 (free base)

References & Citations

[1]Hache G, et al. ARA290, a Specific Agonist of Erythropoietin/CD131 Heteroreceptor, Improves Circulating Endothelial Progenitors' Angiogenic Potential and Homing Ability. Shock. 2016 Oct;46 (4) :390-7.|[2]Carole Muller, et al. ARA290 Improves Insulin Release and Glucose Tolerance in Type 2 Diabetic Goto-Kakizaki Rats. Mol Med. 2015; 21 (1) : 969–978.|[3]Chen H, et al. Therapeutic effects of nonerythropoietic erythropoietin analog ARA290 in experimental autoimmune encephalomyelitis rat. J Neuroimmunol. 2014 Mar 15;268 (1-2) :64-70.