F 991
F 991 is an immunoglobulin free light chain antagonist. F 991 can significantly reduce the levels of pro-inflammatory cytokines (TNF-α and IL-6) . F 991 can be used for research on allergic conditions[1].
Product Specifications
CAS Number
188193-59-1
UNSPSC
12352209
Target
Interleukin Related; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@H](CS)NC([C@H](CS)NC([C@H](CC1=CNC=N1)NC(CNC([C@H](CO)NC([C@H](CC2=CNC3=CC=CC=C23)NC([C@H](CC4=CNC=N4)NC([C@H](C)N)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C43H60N14O11S2
Molecular Weight
1013.15
References & Citations
[1]van Houwelingen AH, et al. Topical application of F991, an immunoglobulin free light chain antagonist, prevents development of contact sensitivity in mice. Clin Exp Allergy. 2007 Feb;37 (2) :270-5.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
IL-6
Frequently Asked Questions
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