F 991

F 991 is an immunoglobulin free light chain antagonist. F 991 can significantly reduce the levels of pro-inflammatory cytokines (TNF-α and IL-6) . F 991 can be used for research on allergic conditions[1].

Product Specifications

CAS Number

[188193-59-1]

UNSPSC

12352209

Target

Interleukin Related; TNF Receptor

Related Pathways

Apoptosis; Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

CC(C)C[C@@H](C(O)=O)NC([C@H](CS)NC([C@H](CS)NC([C@H](CC1=CNC=N1)NC(CNC([C@H](CO)NC([C@H](CC2=CNC3=CC=CC=C23)NC([C@H](CC4=CNC=N4)NC([C@H](C)N)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C43H60N14O11S2

Molecular Weight

1013.15

References & Citations

[1]van Houwelingen AH, et al. Topical application of F991, an immunoglobulin free light chain antagonist, prevents development of contact sensitivity in mice. Clin Exp Allergy. 2007 Feb;37 (2) :270-5.