Palmitoyl Tetrapeptide-3

Palmitoyl Tetrapeptide-3 (Palmitoyl Tetrapeptide-7) is a synthetic peptide corresponding to amino acids 341-344 of the human immunoglobulin heavy chain, with the ability to stimulate phagocytosis. Palmitoyl tetrapeptide-3 reduces interleukin-6 (IL-6) secretion in keratinocytes and inhibits the UVB radiation-exposure inflammatory response of skin. Palmitoyl tetrapeptide-3 It also has anti-inflammatory and anti-aging effects, reducing skin wrinkles by promoting the production of elastic fibers in the papillary dermis[1][2][3][4].

Product Specifications

CAS Number

[221227-05-0]

Product Name Alternative

Palmitoyl Tetrapeptide-7

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Interleukin Related

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Purity

99.20

Solubility

DMF : 10 mg/mL (ultrasonic; adjust pH to 3 with HCl) |H2O : < 0.1 mg/mL (ultrasonic)

Smiles

N=C(N)NCCC[C@@H](C(O)=O)NC([C@H]1N(C([C@H](CCC(N)=O)NC(CNC(CCCCCCCCCCCCCCC)=O)=O)=O)CCC1)=O

Molecular Formula

C34H62N8O7

Molecular Weight

694.91

Precautions

H302, H315, H319, H335

References & Citations

[1]Rocchi R, et al. Synthesis and biological activity of tuftsin and rigin derivatives containing monosaccharides or monosaccharide derivatives. Int J Pept Protein Res. 1987 Feb;29 (2) :262-75.|[2]Schagen S K. Topical peptide treatments with effective anti-aging results[J]. Cosmetics, 2017, 4 (2) : 16.|[3]Mondon P, et al. Evaluation of dermal extracellular matrix and epidermal–dermal junction modifications using matrix‐assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications[J]. Journal of cosmetic dermatology, 2015, 14 (2) : 152-160.|[4]Fengzhu Li, et al. Clinical evidence of the efficacy and safety of a new multi-peptide anti-aging topical eye serum. J Cosmet Dermatol. 2023 Dec;22 (12) :3340-3346.