BIM-23197

BIM-23197 is an SST2 (IC50 = 0.19 nM) agonist. BIM-23197 can effectively stimulate intracellular calcium mobilization in cells expressing SST2. BIM-23197 can be used for research on endocrine related conditions[1].

Product Specifications

CAS Number

[168016-90-8]

UNSPSC

12352209

Target

Somatostatin Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Endocrinology

Smiles

O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC1=O)CCCCN)=O)CC)=O)C(N[C@H](C(N)=O)[C@H](O)C)=O)NC([C@H](NS(CCN2CCN(CC2)CCO)(=O)=O)CC3=CC=CC=C3)=O)=O)CC4=CC=C(C=C4)O)N[C@@H]1CC5=CNC6=CC=CC=C56

Molecular Formula

C57H81N13O13S3

Molecular Weight

1252.53

References & Citations

[1]Tulipano G, et al. Characterization of new selective somatostatin receptor subtype-2 (sst2) antagonists, BIM-23627 and BIM-23454. Effects of BIM-23627 on GH release in anesthetized male rats after short-term high-dose dexamethasone treatment. Endocrinology. 2002 Apr;143 (4) :1218-24.