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Octreotide-d8 (acetate)

Octreotide-d8 (acetate) (SMS 201-995-d8 (acetate) ) is deuterium labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly[1][2].

Product Specifications

Product Name Alternative

SMS 201-995-d8 (acetate)

UNSPSC

12352211

Target

Isotope-Labeled Compounds

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Endocrinology; Inflammation/Immunology; Cardiovascular Disease

Smiles

O=C([C@@H](NC([C@@H](CSSC[C@H](NC([C@](NC([C@@H](NC1=O)CCCCN)=O)([H])[C@H](O)C)=O)C(NC(CO)C(O)C)=O)NC(C(N)([2H])C([2H])([2H])C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=O)=O)CC3=CC=CC=C3)N[C@H]1CC4=CNC5=CC=CC=C45.CC(O)=O

Molecular Formula

C51H62D8N10O12S2

Molecular Weight

1087.34

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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