Echinenone
Echinenone is an acetylcholinesterase (AChE) inhibitor (IC50=16.29 μg/mL) with anti-Aβ (25-35) activity. Echinenone can inhibit MDA content and increase superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) activities to cope with oxidative stress damage[1].
Product Specifications
CAS Number
[432-68-8]
UNSPSC
12352211
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C(C(C)(CC2)C)=C(C)C2=O)=C(C)CCC1
Molecular Formula
C40H54O
Molecular Weight
550.86
References & Citations
[1]Zhang T, et al. Understanding the mechanism of action of echinenone on Alzheimer's disease from the perspective of acetylcholinesterase and oxidative stress[J]. 2022.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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