Procyanidin B2 3′-O-gallate

Procyanidin B2 3′-O-gallate (B2-3′-G), isolated from Rhodiola crenulata extracts, is a potent xanthine oxidase (XO) inhibitor (IC50 = 24.24 μM, Ki = 6.16 μM) . Procyanidin B2 3′-O-gallate has antioxidant activity and reduces the formation of UV-induced α-tocopheroxyl. Procyanidin B2 3′-O-gallate can be used for hyperuricemia and gout research[1][2].

Product Specifications

CAS Number

[73086-04-1]

Product Name Alternative

B2-3′-G; Epicatechin- (4β,8) -epicatechin gallate

UNSPSC

12352005

Target

Xanthine Oxidase

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology; Metabolic Disease

Purity

99.60

Smiles

O[C@@H]1[C@@H](C2=C3C(C[C@H]([C@@H](C4=CC(O)=C(C=C4)O)O3)OC(C5=CC(O)=C(C(O)=C5)O)=O)=C(C=C2O)O)C6=C(O)C=C(O)C=C6O[C@@H]1C7=CC(O)=C(C=C7)O

Molecular Formula

C37H30O16

Molecular Weight

730.62

References & Citations

[1]Lourenço CF, et al. LDL isolated from plasma-loaded red wine procyanidins resist lipid oxidation and tocopherol depletion. J Agric Food Chem. 2008 May 28;56 (10) :3798-804.|[2]Chu YH, et al. Inhibition of xanthine oxidase by Rhodiola crenulata extracts and their phytochemicals. J Agric Food Chem. 2014 Apr 30;62 (17) :3742-9.