12a-Hydroxydalpanol

12a-Hydroxydalpanol is a rotenoid cytotoxic agent found in Amorpha fruticosa. 12a-Hydroxydalpanol exerts cytotoxic effects by inhibiting tumor cell proliferation. 12a-Hydroxydalpanol is promising for research of cancers[1][2].

Product Specifications

CAS Number

[85042-77-9]

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Cancer

Smiles

O[C@@]1([C@](CO2)([H])OC3=C(C[C@@H]4C(C)(O)C)C(O4)=CC=C3C1=O)C(C2=C5)=CC(OC)=C5OC

Molecular Formula

C23H24O8

Molecular Weight

428.43

References & Citations

[1]Li L, et al. Antitumor agents, 138. Rotenoids and isoflavones as cytotoxic constitutents from Amorpha fruticosa. J Nat Prod. 1993 May;56 (5) :690-8.|[2]Terada H, et al. Structural elucidation and chemical conversion of amorphispironone, a novel spironone form Amorpha fruticosa, to rotenoids[J]. Chemical and pharmaceutical bulletin, 1993, 41 (1) : 187-190.