Isopongaflavone
Isopongaflavone is an isoflavone from the seedpods of Tephrosia vogelii with anti-inflammatory effects. Isopongaflavone suppresses the secretion of IL-1β, IFN-γ, granulocyte macrophage-colony stimulating factor (GM-CSF) and TNF-α in LPS -stimulated peripheral blood mononuclear cells (PBMCs).
Product Specifications
CAS Number
64125-33-3
UNSPSC
12352005
Hazard Statement
H410
Target
IFNAR; Interleukin Related; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=C1C=C(OC2=C3C=CC(OC3=CC(OC)=C12)(C)C)C=4C=CC=CC4
Molecular Formula
C21H18O4
Molecular Weight
334.37
Precautions
P273-P391-P501
References & Citations
[1]Owor RO, et al. Isoflavones from the seedpods of Tephrosia vogelii and pyrazoisopongaflavone with anti-inflammatory effects. Fitoterapia. 2020 Oct;146:104695.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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