Betulonaldehyde
Betulonaldehyde is a pentacyclic triterpenoid that can be isolated from Diospyros filipendula. Betulonaldehyde has antiplasmodial activity (IC50: 3.36 µg/mL). Betulonaldehyde has cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s: 19.23 and 17.09 µg/mL, respectively). Betulonaldehyde inhibits Phorbol 12-myristate 13-acetate induced inflammation in mice[1][2].
Product Specifications
CAS Number
4439-98-9
UNSPSC
12352211
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Cancer; Infection; Inflammation/Immunology
Smiles
O=C[C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@]([C@]4([C@]([C@@]5([C@@](C(C)(C(CC5)=O)C)([H])CC4)C)([H])CC3)C)(CC1)C
Molecular Formula
C30H46O2
Molecular Weight
438.69
References & Citations
[1]Wisetsai A, et al. Chemical constituents and their biological activities from the roots of diospyros filipendula. Nat Prod Res. 2021 Aug;35 (16) :2739-2743.|[2]Yasukawa K, et al. Some lupane-type triterpenes inhibit tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. Phytomedicine. 1995 Apr;1 (4) :309-13.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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