Betulonaldehyde

Betulonaldehyde is a pentacyclic triterpenoid that can be isolated from Diospyros filipendula. Betulonaldehyde has antiplasmodial activity (IC50: 3.36 µg/mL) . Betulonaldehyde has cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s: 19.23 and 17.09 µg/mL, respectively) . Betulonaldehyde inhibits Phorbol 12-myristate 13-acetate (HY-18739) induced inflammation in mice[1][2].

Product Specifications

CAS Number

[4439-98-9]

UNSPSC

12352211

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Cancer; Infection; Inflammation/Immunology

Smiles

O=C[C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@]([C@]4([C@]([C@@]5([C@@](C(C)(C(CC5)=O)C)([H])CC4)C)([H])CC3)C)(CC1)C

Molecular Formula

C30H46O2

Molecular Weight

438.69

References & Citations

[1]Wisetsai A, et al. Chemical constituents and their biological activities from the roots of diospyros filipendula. Nat Prod Res. 2021 Aug;35 (16) :2739-2743.|[2]Yasukawa K, et al. Some lupane-type triterpenes inhibit tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. Phytomedicine. 1995 Apr;1 (4) :309-13.