5,7,2',6'-Tetrahydroxyflavone

5,7,2',6'-Tetrahydroxyflavone is a natural flavonoid that inhibits hepatic testosterone 6β-hydroxylation (CYP3A4) activity with an IC50 of 7.8 μM[1].

Product Specifications

CAS Number

[82475-00-1]

UNSPSC

12352005

Target

Cytochrome P450

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Purity

90.0

Solubility

10 mM in DMSO

Smiles

O=C1C=C(C2=C(O)C=CC=C2O)OC3=C1C(O)=CC(O)=C3

Molecular Formula

C15H10O6

Molecular Weight

286.24

References & Citations

[1]Ji-Yeon Kim, et al. Effects of flavonoids isolated from Scutellariae radix on cytochrome P-450 activities in human liver microsomes. J Toxicol Environ Health A. 2002 Mar;65 (5-6) :373-81.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

CYP3

Available Sizes

Curated Selection

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