5,7,2',6'-Tetrahydroxyflavone
5,7,2',6'-Tetrahydroxyflavone is a natural flavonoid that inhibits hepatic testosterone 6β-hydroxylation (CYP3A4) activity with an IC50 of 7.8 μM[1].
Product Specifications
CAS Number
[82475-00-1]
UNSPSC
12352005
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Purity
90.0
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=C(O)C=CC=C2O)OC3=C1C(O)=CC(O)=C3
Molecular Formula
C15H10O6
Molecular Weight
286.24
References & Citations
[1]Ji-Yeon Kim, et al. Effects of flavonoids isolated from Scutellariae radix on cytochrome P-450 activities in human liver microsomes. J Toxicol Environ Health A. 2002 Mar;65 (5-6) :373-81.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CYP3
Available Sizes
Curated Selection
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