Dehydromonocrotaline
Dehydromonocrotaline (Monocrotaline pyrrole) is the metabolite of Monocrotaline (HY-N0750) . Dehydromonocrotaline is an alkylating agent, that reacts with DNA, exhibits cytotoxicity, and induces liver and lung damage[1].
Product Specifications
Product Name Alternative
Monocrotaline pyrrole; MCTP; 3,8-Didehydromonocrotaline
UNSPSC
12352005
Target
DNA Alkylator/Crosslinker
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Smiles
O=C1O[C@@]2([H])C3=C(COC([C@](O)([C@](O)([C@H]1C)C)C)=O)C=CN3CC2
Molecular Formula
C16H21NO6
Molecular Weight
323.34
References & Citations
[1]Mattocks AR, et al., Effects of some pyrrolic and dihydropyrrolizine esters on mouse skin: a preliminary study. Tumori. 1979 Jun 30;65 (3) :289-93.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N9279/
Scientific Category
Natural Products
Clinical Information
No Development Reported
CAS Number
[23291-96-5]
Available Sizes
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DNAJA1, ID (DNAJA1, DNAJ2, HDJ2, HSJ2, HSPF4, DnaJ homolog subfamily A member 1, DnaJ protein homolog 2, HSDJ, Heat shock 40kD protein 4, Heat shock protein J2, Human DnaJ protein 2) (MaxLight 490)