Dehydromonocrotaline

Dehydromonocrotaline (Monocrotaline pyrrole) is the metabolite of Monocrotaline (HY-N0750) . Dehydromonocrotaline is an alkylating agent, that reacts with DNA, exhibits cytotoxicity, and induces liver and lung damage[1].

Product Specifications

CAS Number

[23291-96-5]

Product Name Alternative

Monocrotaline pyrrole; MCTP; 3,8-Didehydromonocrotaline

UNSPSC

12352005

Target

DNA Alkylator/Crosslinker

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Smiles

O=C1O[C@@]2([H])C3=C(COC([C@](O)([C@](O)([C@H]1C)C)C)=O)C=CN3CC2

Molecular Formula

C16H21NO6

Molecular Weight

323.34

References & Citations

[1]Mattocks AR, et al., Effects of some pyrrolic and dihydropyrrolizine esters on mouse skin: a preliminary study. Tumori. 1979 Jun 30;65 (3) :289-93.