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Tunicamycin B

Tunicamycin B is a Tunicamycin (HY-A0098) derivative with antimicrobial activity. Tunicamycin B shows antibacterial activity against Bacillus thuringiensis BT01 and B. thuringiensis W102 (MICs = 0.125 and 0.063 μg/mL, respectively) and antifungal activity against Candida albicans ATCC 96901 and C. albicans CMCC (F) 98001 (MICs = 8.0 and 4.0 μg/mL, respectively) . Tunicamycin B can be used for antimicrobial research[1].

Product Specifications

CAS Number

[66081-36-5]

UNSPSC

12352005

Hazard Statement

H301-H311-H331

Target

Bacterial; Fungal

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C1C=CN([C@@H]2O[C@H]([C@H](O)C[C@H]3O[C@@H](O[C@@H]4[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O4)[C@H](NC(/C=C/CCCCCCCCCCC(C)C)=O)[C@@H](O)[C@H]3O)[C@H](O)[C@@H]2O)C(N1)=O

Molecular Formula

C39H64N4O16

Molecular Weight

844.94

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

References & Citations

[1]Zhang S, et al. Antimicrobial tunicamycin derivatives from the deep sea-derived Streptomyces xinghaiensis SCSIO S15077. Nat Prod Res. 2020 Jun;34 (11) :1499-1504.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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