Dipyrithione (Standard)

Dipyrithione (Standard) is the analytical standard of Dipyrithione (HY-N8432) . This product is intended for research and analytical applications. Dipyrithione is a potent antimicrobial agent. Dipyrithione shows antifungal activity and antiproliferative activity. Dipyrithione induces apoptosis and cycle arrest at G1 phase. Dipyrithione shows anti-inflammatory activity in vivo. Dipyrithione shows anti-tumor activity. Dipyrithione has the potential for the research of dermatophytosis[1][2][3].

Product Specifications

CAS Number

[3696-28-4]

Target

Apoptosis; Bacterial; Fungal; Reference Standards

Related Pathways

Anti-infection; Apoptosis; Others

Field of Research

Cancer; Infection; Inflammation/Immunology

Smiles

[O-][N+]1=CC=CC=C1SSC2=CC=CC=[N+]2[O-]

Molecular Formula

C10H8N2O2S2

Molecular Weight

252.31

References & Citations

[1]Song X, et al. In vivo antifungal activity of dipyrithione against Trichophyton rubrum on guinea pig dermatophytosis models. Biomed Pharmacother. 2018 Dec;108:558-564.|[2]Liu Z, et al. Dipyrithione inhibits lipopolysaccharide-induced iNOS and COX-2 up-regulation in macrophages and protects against endotoxic shock in mice. FEBS Lett. 2008 May 28;582 (12) :1643-50.|[3]Fan Y, et al. Dipyrithione induces cell-cycle arrest and apoptosis in four cancer cell lines in vitro and inhibits tumor growth in a mouse model. BMC Pharmacol Toxicol. 2013 Oct 21;14:54.