Naphthazarin (Standard)

Naphthazarin (DHNQ) is a naturally occurring compound. Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. Naphthazarin triggers apoptosis and has anti-tumor effects[1][2].

Product Specifications

CAS Number

[475-38-7]

UNSPSC

12352005

Target

Apoptosis

Related Pathways

Apoptosis

Field of Research

Cancer; Neurological Disease

Smiles

O=C1C=CC(C2=C1C(O)=CC=C2O)=O

Molecular Formula

C10H6O4

Molecular Weight

190.15

References & Citations

[1]Seon Young Choi, et al. Naphthazarin has a protective effect on the 1-methyl-4-phenyl-1,2,3,4-tetrahydropyridine-induced Parkinson's disease model. J Neurosci Res. 2012 Sep;90 (9) :1842-9.|[2]Omar Aljanadi, et al. Stimulation of Suicidal Erythrocyte Death by Naphthazarin. Basic Clin Pharmacol Toxicol. 2015 Dec;117 (6) :369-74.