N-acetyldopamine (Standard)
N-acetyldopamine is a sepiapterin reductase inhibitor. N-acetyldopamine is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle. N-acetyldopamine can attenuate LPS-stimulated TNF-α production and superoxide production in THP-1 cells[1][2].
Product Specifications
CAS Number
2494-12-4
UNSPSC
12352005
Target
Endogenous Metabolite; Reactive Oxygen Species (ROS) ; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Others
Smiles
CC(NCCC1=CC=C(O)C(O)=C1)=O
Molecular Formula
C10H13NO3
Molecular Weight
195.22
References & Citations
[1]Hanine Barek, et al. Unraveling Complex Molecular Transformations of N-β-alanyldopamine That Account for Brown Coloration of Insect Cuticle. Rapid Commun Mass Spectrom. 2017 Aug 30;31 (16) :1363-1373.|[2]Perianayagam, M. C., et al., (2005) . Immune-modulating effects of melatonin, N-acetylserotonin, and N-acetyldopamine. Annals of the New York Academy of Sciences, 1053, 386–393.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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