Ethyl Caffeate (Standard)
Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].
Product Specifications
CAS Number
[102-37-4]
UNSPSC
12352005
Target
COX; NF-κB; NO Synthase; PGE synthase
Related Pathways
Immunology/Inflammation; NF-κB
Field of Research
Inflammation/Immunology; Cancer
Smiles
O=C(OCC)/C=C/C1=CC=C(O)C(O)=C1
Molecular Formula
C11H12O4
Molecular Weight
208.21
References & Citations
[1]Chiang YM, et al. Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br J Pharmacol. 2005 Oct;146 (3) :352-63.
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