Cytochalasin E (Standard)

Antazoline (phosphate) (Standard) is the analytical standard of Antazoline (phosphate) . This product is intended for research and analytical applications. Antazoline phosphate is an H1 receptor antagonist that affects the activity of the central nervous system, has a potent antiarrhythmic effect[1][2][3].

Product Specifications

CAS Number

[36011-19-5]

UNSPSC

12352005

Target

Autophagy; Reference Standards

Related Pathways

Autophagy; Others

Field of Research

Cancer

Smiles

O=C1[C@]2(O3)[C@]([C@@H]([C@](O4)(C)[C@@H]4[C@]2([H])/C=C/C[C@@H](C([C@](C)(O)/C=C/OC3=O)=O)C)C)([H])[C@H](CC5=CC=CC=C5)N1

Molecular Formula

C28H33NO7

Molecular Weight

495.56

References & Citations

[1]Udagawa T, et al. Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesisand tumor growth. J Pharmacol Exp Ther. 2000 Aug;294 (2) :421-7.|[2]Lu QY, et al. Green tea extract modulates actin remodeling via Rho activity in an in vitro multistep carcinogenicmodel. Clin Cancer Res. 2005 Feb 15;11 (4) :1675-83.|[3]Takanezawa Y, et al. Variation in the activity of distinct cytochalasins as autophagy inhibitiors in human lung A549 cells. Biochem Biophys Res Commun. 2017 Dec 16;494 (3-4) :641-647.