Nocathiacin I

Nocathiacin I (Nocathiacine I) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) [1].

Product Specifications

CAS Number

[214044-52-7]

Product Name Alternative

Nocathiacine I

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

ON1C2=CC=CC(COC3=O)=C2C(CO[C@@]([C@@H]3O[C@H](O[C@H]4C)C[C@](O)([C@@H]4N(C)C)C)([H])[C@@](NC(C5=CSC(/C(NC([C@](N6)([H])[C@H](O)C)=O)=C(C)\OC)=N5)=O)([H])C7=NC8=CS7)=C1C(OC[C@@](NC8=O)([H])C9=NC(C(C(C%10=NC(C6=O)=CS%10)=C%11)=NC(C%12=NC(C(NC(C(N)=O)=C)=O)=CS%12)=C%11O)=CS9)=O

Molecular Formula

C61H60N14O18S5

Molecular Weight

1437.54

References & Citations

[1]Sheo B Singh, et al. Nocathiacin, Thiazomycin, and Polar Analogs Are Highly Effective Agents against Toxigenic Clostridioides difficile. J Nat Prod. 2022 Apr 22;85 (4) :1141-1146.