Nocathiacin II

Nocathiacin II (Nocathiacine II) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) [1].

Product Specifications

CAS Number

[256230-46-3]

Product Name Alternative

Nocathiacine II

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=C(OC[C@@](NC1=O)([H])C2=NC(C(C(C3=NC(C4=O)=CS3)=C5)=NC(C6=NC(C(NC(C(N)=O)=C)=O)=CS6)=C5O)=CS2)C7=C(CO[C@@]([C@@H]8O[C@H](O[C@H]9C)C[C@](O)([C@@H]9N(C)C)C)([H])[C@@](NC(C%10=CSC(/C(NC([C@](N4)([H])[C@H](O)C)=O)=C(C)\OC)=N%10)=O)([H])C%11=NC1=CS%11)C(C(N7)=CC=C%12)=C%12COC8=O

Molecular Formula

C61H60N14O17S5

Molecular Weight

1421.54

References & Citations

[1]Sheo B Singh, et al. Nocathiacin, Thiazomycin, and Polar Analogs Are Highly Effective Agents against Toxigenic Clostridioides difficile. J Nat Prod. 2022 Apr 22;85 (4) :1141-1146.