Lipohexin
Lipohexin is a peptide antibiotic. Lipohexin has anti-Gram-positive bacterial effect. Lipohexin had competitive inhibitory effect on human placental proline endopeptidase with an IC50 of 3.5 μM. Lipohexin inhibits the proline endopeptidase from the Flavobacterium meningoseptiu with an IC50 of 25 μM[1].
Product Specifications
CAS Number
[193751-58-5]
UNSPSC
12352005
Target
Antibiotic; Bacterial; Prolyl Endopeptidase (PREP)
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
OC(CCNC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC([C@H]1N(CCC1)C(C(C)C(CCCCCCCCCCC)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C39H68N6O9
Molecular Weight
764.99
References & Citations
[1]S Heinze, et al. Lipohexin, a new inhibitor of prolyl endopeptidase from Moeszia lindtneri (HKI-0054) and Paecilomyces sp. (HKI-0055; HKI-0096) . I. Screening, isolation and structure elucidation. J Antibiot (Tokyo) . 1997 May;50 (5) :379-83.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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