Lipohexin

Lipohexin is a peptide antibiotic. Lipohexin has anti-Gram-positive bacterial effect. Lipohexin had competitive inhibitory effect on human placental proline endopeptidase with an IC50 of 3.5 μM. Lipohexin inhibits the proline endopeptidase from the Flavobacterium meningoseptiu with an IC50 of 25 μM[1].

Product Specifications

CAS Number

[193751-58-5]

UNSPSC

12352005

Target

Antibiotic; Bacterial; Prolyl Endopeptidase (PREP)

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

OC(CCNC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC([C@H]1N(CCC1)C(C(C)C(CCCCCCCCCCC)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C39H68N6O9

Molecular Weight

764.99

References & Citations

[1]S Heinze, et al. Lipohexin, a new inhibitor of prolyl endopeptidase from Moeszia lindtneri (HKI-0054) and Paecilomyces sp. (HKI-0055; HKI-0096) . I. Screening, isolation and structure elucidation. J Antibiot (Tokyo) . 1997 May;50 (5) :379-83.