Cypemycin
Cypemycin is a linaridin antibiotic that can inhibit cancer cell activity, inhibits P388 leukemia cells with IC50 of 1.3 μg/mL. Cypemycin can inhibit human tumor cells such as HeLa S3, HHCC-1, HCCS-M and Slex with IC50 of >25 μg/mL[1].
Product Specifications
CAS Number
[154277-21-1]
UNSPSC
12352005
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Smiles
O=C(N[C@H](C(N[C@H](C(N/C=C\SC1)=O)C(C)C)=O)CC(C)C)[C@H]1NC([C@H]([C@H](C)CC)NC(/C(NC([C@H](CO)NC(CNC([C@H](CCC(N)=O)NC([C@H]([C@H](C)CC)NC([C@H](C(C)C)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](C(C)C)NC(/C(NC([C@H]3N(CCC3)C(/C(NC([C@H](C)NC([C@H]4N(CCC4)C(/C(NC([C@H](C)N(C)C)=O)=C\C)=O)=O)=O)=C\C)=O)=O)=C\C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=C\C)=O)=O
Molecular Formula
C99H154N24O24S
Molecular Weight
2096.49
References & Citations
[1]Wei Ding, et al. Substrate specificity of the cypemycin decarboxylase CypD. Synth Syst Biotechnol. 2018 Sep 15;3 (3) :159-162.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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