Arborcandin B

Arborcandin B is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin B exhibits IC50 values of 0.30 μg/mL and 0.025 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin B has an MIC of 2-4 μg/mL against the genus Candida[1].

Product Specifications

CAS Number

[223465-78-9]

UNSPSC

12352211

Target

Antibiotic; Fungal

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

NC(C(O)CC1C(N[C@](C(N[C@@](C(NC(C(NCC(NCCC(NC(C(N[C@@H](C(N[C@H](C(N[C@@H](C(N1)=O)C)=O)CC(N)=O)=O)CC(N)=O)=O)CCCCCCCC(O)CCCCC)=O)=O)=O)CCC(O)CCCCCCCCC)=O)([H])[C@H](O)C)=O)([H])[C@H](O)C)=O)=O

Molecular Formula

C58H103N13O18

Molecular Weight

1270.51

References & Citations

[1]Ohyama T, et al. Arborcandins A, B, C, D, E and F, novel 1, 3-β-glucan synthase inhibitors: Production and biological activity[J]. The Journal of Antibiotics, 2000, 53 (10) : 1108-1116.