Arborcandin A

Arborcandin A is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin A exhibits IC50 values of 0.25 μg/mL and 0.05 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin A has an MIC of 4-8 μg/mL against the genus Candida[1].

Product Specifications

CAS Number

[223465-76-7]

UNSPSC

12352211

Target

Antibiotic; Fungal

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

NC(C(O)CC(NC([C@@H](C)NC([C@H](CC(N)=O)NC([C@@H](CC(N)=O)NC(C(CCCCCCCC(O)CCCC)NC(CCN1)=O)=O)=O)=O)=O)C(N[C@]([C@H](O)C)(C(N[C@@]([C@H](O)C)(C(NC(C(NCC1=O)=O)CCC(O)CCCCCCCCC)=O)[H])=O)[H])=O)=O

Molecular Formula

C57H101N13O18

Molecular Weight

1256.49

References & Citations

[1]Ohyama T, et al. Arborcandins A, B, C, D, E and F, novel 1, 3-β-glucan synthase inhibitors: Production and biological activity[J]. The Journal of Antibiotics, 2000, 53 (10) : 1108-1116.